The antibody detects endogenous levels of total BMP8A protein.
Applications:
WB, IF
Reactivity:
Human
Immunogen:
Synthesized peptide derived from C-terminal of human BMP8A.
Host:
Rabbit
Clonality:
Polyclonal
Conjugate:
Unconjugated
Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:
1.0mg / ml
Formulation:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage:
Store at -20?C
Target
Function:
Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis (By similarity). Signaling protein involved in regulation of thermogenesis and energy balance. Proposed to increase the peripheral response of brown adipose tissue (BAT) to adrenergic stimulation while acting centrally in the hypothalamus to increase sympathetic output to BAT.
Sequence Similarities:
Belongs to the TGF-beta family.
Cellular Location:
Secreted.
Database Links:
Entrez Gene: 353500?Human
SwissProt: Q7Z5Y6?Human
Unigene: 472497?Human
Synonyms:
BMP-8A Antibody
BMP8 Antibody
BMP8a Antibody
BMP8A_HUMAN Antibody
Bone morphogenetic protein 8A Antibody
FLJ14351 Antibody
FLJ45264 Antibody
OP 2 Antibody
Osteogenic protein 2 Antibody
Information:
Target information shown above is from the UniProt Consortium.