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Anti-BMP4 Antibody

品牌：Antibodies

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規(guī)格：50μl

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Anti-BMP4 Antibody

商品詳情參考文獻(xiàn) 相關(guān)資料

Overview

Name:	Anti-BMP4 Antibody See all BMP4 primary antibodies
Description:	Rabbit polyclonal antibody to BMP4
Specificity:	BMP4 pAb detects endogenous levels of BMP4 protein.
Applications:	WB, IHC
Reactivity:	Human, Mouse, Rat
Immunogen:	Recombinant full length Human BMP4.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Molecular Weight:	~ 47 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form:	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Target

Function:	Induces cartilage and bone formation. Also act in mesoderm induction, tooth development, limb formation and fracture repair. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity).
Tissue Specificity:	Expressed in the lung and lower levels seen in the kidney. Present also in normal and neoplastic prostate tissues, and prostate cancer cell lines.
Involvement in Disease:	Microphthalmia, syndromic, 6: A disease characterized by microphthalmia/anophthalmia associated with facial, genital, skeletal, neurologic and endocrine anomalies. Microphthalmia is a disorder of eye formation, ranging from small size of a single eye to complete bilateral absence of ocular tissues (anophthalmia). In many cases, microphthalmia/anophthalmia occurs in association with syndromes that include non-ocular abnormalities. Non-syndromic orofacial cleft 11: A birth defect consisting of cleft lips with or without cleft palate. Cleft lips are associated with cleft palate in two-third of cases. A cleft lip can occur on one or both sides and range in severity from a simple notch in the upper lip to a complete opening in the lip extending into the floor of the nostril and involving the upper gum.
Sequence Similarities:	Belongs to the TGF-beta family.
Cellular Location:	Secreted > Extracellular space > Extracellular matrix.
Database Links:	Entrez Gene: 652?Human Entrez Gene: 12159?Mouse Entrez Gene: 25296?Rat Omim: 112262?Human SwissProt: P12644?Human SwissProt: P21275?Mouse SwissProt: Q06826?Rat Unigene: 68879?Human Unigene: 6813?Mouse Unigene: 10318?Rat
Synonyms:	zgc:100779 Antibody BMP 2B Antibody BMP 4 Antibody BMP-2B Antibody BMP-4 Antibody BMP2B Antibody BMP2B1 Antibody BMP4 Antibody BMP4_HUMAN Antibody BOMPR4A Antibody Bone morphogenetic protein 2B Antibody Bone morphogenetic protein 4 Antibody DVR4 Antibody MCOPS6 Antibody MGC100779 Antibody OFC11 Antibody OTTMUSP00000021065 Antibody OTTMUSP00000021066 Antibody zbmp-4 Antibody ZYME Antibody
Information:	Target information shown above is from the UniProt Consortium.