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Anti-BIK (M27) Antibody

品牌：Antibodies

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規(guī)格：50μl

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Anti-BIK (M27) Antibody

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Name:	Anti-BIK (M27) Antibody See all BIK primary antibodies
Description:	Rabbit polyclonal antibody to BIK (M27)
Specificity:	BIK (M27)pAb detects endogenous levels of BIK protein
Applications:	WB, IHC, IF
Reactivity:	Human, Mouse, Rat
Immunogen:	Synthetic peptide, corresponding to the N-terminal of Human BIK.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Molecular Weight:	~ 23 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form:	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Function:	Accelerates programmed cell death. Association to the apoptosis repressors Bcl-X(L), BHRF1, Bcl-2 or its adenovirus homolog E1B 19k protein suppresses this death-promoting activity. Does not interact with BAX.
Post-Translational Modification:	Proteolytically cleaved by RHBDL4/RHBDD1. RHBDL4/RHBDD1-induced cleavage is a necessary step prior its degradation by the proteosome-dependent mechanism.
Cellular Location:	Endomembrane system. Mitochondrion membrane. Around the nuclear envelope, and in cytoplasmic membranes.
Database Links:	Entrez Gene: 638?Human Entrez Gene: 12124?Mouse Entrez Gene: 114496?Rat Omim: 603392?Human SwissProt: Q13323?Human SwissProt: O70337?Mouse Unigene: 475055?Human
Synonyms:	Apoptosis inducer NBK Antibody BBC1 Antibody Bcl-2-interacting killer Antibody BCL2 interacting killer Antibody bhikhari Antibody Bik Antibody Bik-like killer protein Antibody BIK_HUMAN Antibody BIP 1 Antibody BiP1 Antibody BP 4 Antibody BP4 Antibody cb 60 Antibody NBK Antibody
Information:	Target information shown above is from the UniProt Consortium.