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Anti-BAP31 Antibody

品牌：Antibodies

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規(guī)格：50μl

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Anti-BAP31 Antibody

商品詳情參考文獻(xiàn) 相關(guān)資料

Overview

Name:	Anti-BAP31 Antibody See all BAP31 primary antibodies
Description:	Rabbit polyclonal antibody to BAP31
Specificity:	BAP31 Polyclonal Antibody detects endogenous levels of BAP31 protein.
Applications:	WB, ELISA
Reactivity:	Human, Mouse, Rat
Immunogen:	Synthesized peptide derived from the Internal region of human BAP31.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1mg / ml
Formulation:	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage:	Store at -20?C / 1 year

Target

Function:	Functions as a chaperone protein. Is one of the most abundant endoplasmic reticulum (ER) proteins. Plays a role in the export of secreted proteins in the ER, the recognition of abnormally folded protein and their targeting to the ER associated-degradation (ERAD). Also serves as a cargo receptor for the export of transmembrane proteins. May be involved in CASP8-mediated apoptosis.
Tissue Specificity:	Ubiquitous. Highly expressed in neurons and discrete endocrine cells.
Involvement in Disease:	Deafness, dystonia, and cerebral hypomyelination: An X-linked recessive mental retardation syndrome characterized by almost no psychomotor development, dysmorphic facial features, sensorineural deafness, dystonia, pyramidal signs, and hypomyelination on brain imaging.
Sequence Similarities:	Belongs to the BCAP29/BCAP31 family.
Post-Translational Modification:	Cleaved by CASP8 and other caspases.
Cellular Location:	Endoplasmic reticulum membrane. Endoplasmic reticulum-Golgi intermediate compartment membrane. May shuttle between the ER and the intermediate compartment/cis-Golgi complex.
Database Links:	Entrez Gene: 10134?Human Entrez Gene: 27061?Mouse Entrez Gene: 293852?Rat Omim: 300398?Human SwissProt: P51572?Human SwissProt: Q61335?Mouse Unigene: 522817?Human Unigene: 17?Mouse Unigene: 96419?Rat
Synonyms:	6C6 AG Antibody 6C6 AG tumor associated antigen Antibody 6C6-AG tumor-associated antigen Antibody 6C6AG Antibody 6C6AG tumor associated antigen Antibody Accessory protein BAP 31 Antibody Accessory protein BAP31 Antibody B cell receptor associated protein 31 Antibody B-cell receptor-associated protein 31 Antibody BA31 Antibody BAP 31 Antibody BAP31 Antibody BAP31_HUMAN Antibody BCAP 31 Antibody BCAP31 Antibody BCR associated protein Bap 31 Antibody BCR associated protein Bap31 Antibody BCR-associated protein 31 Antibody CDM Antibody CDM protein Antibody DXS1357E Antibody MS950 Antibody p28 Antibody p28 Bap31 Antibody Protein CDM Antibody RP23-329M9.5 Antibody
Information:	Target information shown above is from the UniProt Consortium.