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Anti-BANP Antibody

品牌：Antibodies

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規(guī)格：100μl

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Anti-BANP Antibody

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Overview

Name:	Anti-BANP Antibody See all BANP primary antibodies
Description:	Rabbit polyclonal antibody to BANP
Applications:	E, WB, IHC
Reactivity:	Human, Mouse, Rat
Immunogen:	Raised against a 14 amino acid peptide near the center of human BANP.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Affinity chromatography purified via peptide column
Formulation:	Supplied in PBS containing 0.02% sodium azide.
Storage:	Can be stored at -20?C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target

Function:	Controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function. Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest and inhibits tumor growth.
Tissue Specificity:	Highly expressed in heart, spleen, and thymus. Isoform 1 is highly expressed in kidney, brain and testis. Isoform 3 is highly expressed in kidney and lung.
Sequence Similarities:	Belongs to the BANP/SMAR1 family.
Cellular Location:	Nucleus.
Database Links:	Entrez Gene: 54971?Human Entrez Gene: 53325?Mouse Entrez Gene: 292064?Rat Omim: 611564?Human SwissProt: Q8N9N5?Human SwissProt: Q8VBU8?Mouse Unigene: 461705?Human Unigene: 287163?Mouse
Synonyms:	AAH09424 Antibody BANP Antibody BANP_HUMAN Antibody BEN domain-containing protein 1 Antibody BEND1 Antibody BTG3 associated nuclear protein isoform a Antibody Btg3-associated nuclear protein Antibody DKFZp761H172 Antibody FLJ 10177 Antibody FLJ 20538 Antibody FLJ10177 Antibody FLJ20538 Antibody Protein BANP Antibody Scaffold/Matrix associated region 1 Antibody Scaffold/matrix-associated region-1-binding protein Antibody SMAR 1 Antibody SMAR1 Antibody SMARBP 1 Antibody SMARBP1 Antibody
Information:	Target information shown above is from the UniProt Consortium.