The antibody detects endogenous levels of total AUP1 protein.
Applications:
WB, IHC
Reactivity:
Human
Immunogen:
Fusion protein corresponding to residues near the C terminal of human ancient ubiquitous protein 1
Host:
Rabbit
Clonality:
Polyclonal
Conjugate:
Unconjugated
Purification:
Antigen affinity purification.
Concentration:
1.9mg / ml
Formulation:
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage:
Store at -20?C
Target
Function:
May play a role in the translocation of terminally misfolded proteins from the endoplasmic reticulum lumen to the cytoplasm and their degradation by the proteasome.
Tissue Specificity:
Detected in blood platelets and leukocytes (at protein level). Ubiquitous. Highly expressed in placenta, liver, kidney, skeletal muscle, heart and brain.
Sequence Similarities:
Belongs to the AUP1 family.
Cellular Location:
Endoplasmic reticulum membrane.
Database Links:
Entrez Gene: 550?Human
Omim: 602434?Human
SwissProt: Q9Y679?Human
Unigene: 411480?Human
Synonyms:
AA589454 Antibody
Ancient ubiquitous protein 1 Antibody
AUP 1 Antibody
aup1 Antibody
AUP1_HUMAN Antibody
Information:
Target information shown above is from the UniProt Consortium.