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Anti-ATP5A1 Antibody

品牌：Antibodies

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規(guī)格：100μg

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Anti-ATP5A1 Antibody

商品詳情參考文獻相關(guān)資料

Overview

Name:	Anti-ATP5A1 Antibody See all ATP5A1 primary antibodies
Description:	Goat polyclonal antibody to ATP5A1.
Applications:	ELISA, WB
Reactivity:	Human, Mouse, Rat, Porcine
Immunogen:	Synthetic peptide corresponding to Human ATP5A1 (internal region).
Sequence:	C-RVHGLRNVQAEE
Host:	Goat
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	100 μg at 0.5 mg/ml.
Product Form:	Liquid
Formulation:	Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

Function:	Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Subunits alpha and beta form the catalytic core in F(1). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits. Subunit alpha does not bear the catalytic high-affinity ATP-s (By similarity).
Tissue Specificity:	Expressed in flagella of epididymal sperm.
Sequence Similarities:	Belongs to the ATPase alpha/beta chains family.
Post-Translational Modification:	Acetylated on lysine residues. BLOC1S1 is required for acetylation (By similarity).
Cellular Location:	Mitochondrion inner membrane. Cell membrane. Colocalizes with HRG on the cell surface of T-cells.
Database Links:	Entrez Gene: 498?Human Entrez Gene: 11946?Mouse Entrez Gene: 100157880?Pig Entrez Gene: 65262?Rat Omim: 164360?Human SwissProt: P25705?Human SwissProt: Q03265?Mouse SwissProt: P80021?Pig SwissProt: P15999?Rat Unigene: 298280?Human Unigene: 276137?Mouse Unigene: 474505?Mouse Unigene: 40255?Rat
Synonyms:	ATP synthase alpha chain, mitochondrial Antibody ATP synthase subunit alpha Antibody ATP synthase subunit alpha mitochondrial Antibody ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle Antibody ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit, 1 Antibody ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit, isoform 1, cardiac muscle Antibody ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit, isoform 2, non-cardiac muscle-like 2 Antibody ATP sythase (F1 ATPase) alpha subunit Antibody ATP5A Antibody Atp5a1 Antibody ATP5AL2 Antibody ATPA_HUMAN Antibody ATPM Antibody Epididymis secretory sperm binding protein Li 123m Antibody hATP1 Antibody HEL-S-123m Antibody MC5DN4 Antibody mitochondrial Antibody Mitochondrial ATP synthetase Antibody Mitochondrial ATP synthetase oligomycin resistant Antibody Modifier of Min 2 mouse homolog Antibody Modifier of Min 2, mouse, homolog of Antibody MOM2 Antibody OMR Antibody ORM Antibody OTTHUMP00000163475 Antibody
Information:	Target information shown above is from the UniProt Consortium.