国产欧美日韩A片免费软件,国产精品99精品久久免费

您好，歡迎來(lái)到拜力生物網(wǎng)站！請(qǐng)登錄注冊(cè)

我的訂單 | 聯(lián)系我們 | 在線(xiàn)客服QQ：3012681483 | 客服電話(huà)：400-968-7988 | 工作時(shí)間：08:30-17:30

主營(yíng)產(chǎn)品： ELISA試劑盒、抗體、補(bǔ)體血清、兔補(bǔ)體、干擾素、小鼠測(cè)溫儀、進(jìn)口試劑、Quidel代理、Swant代理、PBL Assay Science代理

網(wǎng)站首頁(yè) 產(chǎn)品中心代理品牌新聞資訊資源中心關(guān)于我們

所在位置：首頁(yè) > 產(chǎn)品中心 > Antibodies > Antibodies產(chǎn)品

訂購(gòu)信息

上海拜力生物科技公司

Tel:400-968-7988 021-33779008

Anti-ATF6 Antibody

品牌：Antibodies

貨號(hào)：

規(guī)格：100μl

貨期：

應(yīng)用：

咨詢(xún)客服

立即購(gòu)買(mǎi) 加入購(gòu)物車(chē)

Anti-ATF6 Antibody

商品詳情參考文獻(xiàn) 相關(guān)資料

Overview

Name:	Anti-ATF6 Antibody See all ATF6 primary antibodies
Description:	Rabbit polyclonal antibody to ATF6
Specificity:	The antibody detects endogenous levels of total ATF6 protein.
Applications:	IHC
Dilutions:	Immunohistochemistry: 1:20-1:100
Reactivity:	Human
Immunogen:	Synthetic peptide of human ATF6
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Antigen affinity purification.
Concentration:	1.5mg / ml
Formulation:	Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Storage:	Store at -20?C

Target

Function:	Transmembrane glycoprotein of the endoplasmic reticulum that functions as a transcription activator and initiates the unfolded protein response (UPR) during endoplasmic reticulum stress. Cleaved upon ER stress, the N-terminal processed cyclic AMP-dependent transcription factor ATF-6 alpha translocates to the nucleus where it activates transcription of genes involved in the UPR. Binds DNA on the 5'-CCAC[GA]-3'half of the ER stress response element (ERSE) (5'-CCAAT-N(9)-CCAC[GA]-3') and of ERSE II (5'-ATTGG-N-CCACG-3'). Binding to ERSE requires binding of NF-Y to ERSE. Could also be involved in activation of transcription by the serum response factor. May play a role in foveal development and cone function in the retina.
Tissue Specificity:	Ubiquitous.
Involvement in Disease:	Achromatopsia 7: A form of achromatopsia, an ocular stationary disorder due to the absence of functioning cone photoreceptors in the retina. It is characterized by total colorblindness, low visual acuity, photophobia and nystagmus.
Sequence Similarities:	Belongs to the bZIP family. ATF subfamily.
Post-Translational Modification:	During unfolded protein response an approximative 50 kDa fragment containing the cytoplasmic transcription factor domain is released by proteolysis. The cleavage seems to be performed sequentially by site-1 and site-2 proteases.
Cellular Location:	Endoplasmic reticulum membrane.
Database Links:	Entrez Gene: 22926?Human Omim: 605537?Human SwissProt: P18850?Human Unigene: 492740?Human
Synonyms:	Activating transcription factor 6 Antibody Activating transcription factor 6 alpha Antibody ATF 6 Antibody ATF6 Antibody ATF6 alpha Antibody ATF6-alpha Antibody ATF6A Antibody ATF6A_HUMAN Antibody cAMP dependent transcription factor ATF 6 alpha Antibody cAMP-dependent transcription factor ATF-6 alpha Antibody Cyclic AMP dependent transcription factor ATF 6 alpha Antibody DKFZp686P2194 Antibody ESTM49 Antibody FLJ21663 Antibody Processed cyclic AMP dependent transcription factor ATF 6 alpha Antibody Processed cyclic AMP-dependent transcription factor ATF-6 alpha Antibody
Information:	Target information shown above is from the UniProt Consortium.