Rabbit polyclonal ASRGL1 (1) antibody was raised against a recombinated human ASRGL1 protein 2-180aa (BC064963).
Host:
Rabbit
Clonality:
Polyclonal
Conjugate:
Unconjugated
Purification:
Affinity purified
Concentration:
1.0mg / ml
Formulation:
PBS, pH 7.4 with 0.02% Sodium Azide
Storage:
This product is stable for several weeks at 4?C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20?C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Target
Function:
Has both L-asparaginase and beta-aspartyl peptidase activity. May be involved in the production of L-aspartate, which can act as an excitatory neurotransmitter in some brain regions. Is highly active with L-Asp beta-methyl ester. Besides, has catalytic activity toward beta-aspartyl dipeptides and their methyl esters, including beta-L-Asp-L-Phe, beta-L-Asp-L-Phe methyl ester (aspartame), beta-L-Asp-L-Ala, beta-L-Asp-L-Leu and beta-L-Asp-L-Lys. Does not have aspartylglucosaminidase activity and is inactive toward GlcNAc-L-Asn. Likewise, has no activity toward glutamine.
Tissue Specificity:
Expressed in brain, kidney, testis and tissues of the gastrointestinal tract. Present in sperm (at protein level). Over-expressed in uterine, mammary, prostatic and ovarian carcinoma.
Sequence Similarities:
Belongs to the Ntn-hydrolase family.
Post-Translational Modification:
Cleaved into an alpha and beta chain by autocatalysis; this activates the enzyme. The N-terminal residue of the beta subunit is responsible for the nucleophile hydrolase activity.
Cellular Location:
Cytoplasm.
Midpiece of sperm tail.
Database Links:
Entrez Gene: 80150?Human
Omim: 609212?Human
SwissProt: Q7L266?Human
Unigene: 535326?Human
Synonyms:
ALP Antibody
ALP1 Antibody
ASGL1 Antibody
Asparaginase like 1 Antibody
Asparaginase like 1 protein Antibody
Asparaginase like protein 1 Antibody
ASRGL 1 Antibody
ASRGL1 Antibody
beta-aspartyl-peptidase Antibody
CRASH Antibody
FLJ22316 Antibody
isoaspartyl dipeptidase Antibody
isoaspartyl peptidase/L-asparaginase Antibody
L asparaginase Antibody
L asparagine amidohydrolase Antibody
Information:
Target information shown above is from the UniProt Consortium.