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Anti-SLC27A5 Antibody

品牌：Antibodies

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規(guī)格：50μl

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Anti-SLC27A5 Antibody

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Overview

Name:	Anti-SLC27A5 Antibody See all SLC27A5 primary antibodies
Description:	Rabbit polyclonal antibody to SLC27A5
Specificity:	The antibody detects endogenous levels of total SLC27A5 protein.
Applications:	WB, IHC, IF
Reactivity:	Human
Immunogen:	Synthesized peptide derived from internal of human SLC27A5.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1.0mg / ml
Formulation:	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage:	Store at -20?C

Target

Function:	Acyl-CoA synthetase involved in bile acid metabolism. Proposed to catalyze the first step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi by activating them to their CoA thioesters. Seems to activate secondary bile acids entering the liver from the enterohepatic circulation. In vitro, also activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol.
Tissue Specificity:	Predominantly expressed in liver.
Sequence Similarities:	Belongs to the ATP-dependent AMP-binding enzyme family.
Cellular Location:	Endoplasmic reticulum membrane.
Database Links:	Entrez Gene: 10998?Human Omim: 603314?Human SwissProt: Q9Y2P5?Human Unigene: 292177?Human
Synonyms:	ACSB Antibody ACSVL6 Antibody BA CoA ligase Antibody BA-CoA ligase Antibody BACS Antibody BAL Antibody Bile acid CoA ligase Antibody Bile acid-CoA ligase Antibody Bile acyl CoA synthetase Antibody Bile acyl-CoA synthetase Antibody Cholate CoA ligase Antibody Cholate--CoA ligase Antibody FACVL3 Antibody FATP 5 Antibody FATP-5 Antibody FATP5 Antibody Fatty acid Coenzyme A ligase very long chain 3 Antibody Fatty acid transport protein 5 Antibody Fatty-acid-coenzyme A ligase Antibody FLJ22987 Antibody S27A5_HUMAN Antibody SLC27A5 Antibody Solute carrier family 27 (fatty acid transporter) member 5 Antibody Solute carrier family 27 member 5 Antibody Very long chain acyl CoA synthetase homolog 2 Antibody Very long chain acyl CoA synthetase related protein Antibody very long-chain 3 Antibody Very long-chain acyl-CoA synthetase homolog 2 Antibody Very long-chain acyl-CoA synthetase-related protein Antibody VLACS related Antibody VLACS-related Antibody VLACSR Antibody VLCS H2 Antibody VLCS-H2 Antibody VLCSH2 Antibody
Information:	Target information shown above is from the UniProt Consortium.