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Anti-SLC12A6 Antibody

品牌：Antibodies

貨號：

規(guī)格：100μg

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Anti-SLC12A6 Antibody

商品詳情參考文獻相關(guān)資料

Overview

Name:	Anti-SLC12A6 Antibody See all SLC12A6 primary antibodies
Description:	Goat polyclonal antibody to SLC12A6.
Applications:	ELISA, WB, IHC
Reactivity:	Human
Immunogen:	Synthetic peptide corresponding to Human SLC12A6 (internal region).
Sequence:	SRHIDVCSKTKE
Host:	Goat
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	100 μg at 0.5 mg/ml.
Product Form:	Liquid
Formulation:	Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

Function:	Mediates electroneutral potassium-chloride cotransport. May be activated by cell swelling. May contribute to cell volume homeostasis in single cells.
Tissue Specificity:	Highly expressed in heart, brain and kidney. Detected at lower levels in skeletal muscle, placenta, lung and pancreas. Detected in umbilical vein endothelial cells. Isoform 2 is more abundant in kidney. Isoform 5 is testis specific. Expressed in the proximal tubule of the kidney (at protein level).
Involvement in Disease:	Agenesis of the corpus callosum, with peripheral neuropathy: A disease that is characterized by severe progressive sensorimotor neuropathy, mental retardation, dysmorphic features and complete or partial agenesis of the corpus callosum.
Sequence Similarities:	Belongs to the SLC12A transporter family.
Post-Translational Modification:	N-glycosylated.
Cellular Location:	Basolateral cell membrane.
Database Links:	Entrez Gene: 9990?Human Omim: 604878?Human SwissProt: Q9UHW9?Human Unigene: 510939?Human
Synonyms:	ACCPN Antibody Electroneutral potassium-chloride cotransporter 3 Antibody Furosemide sensitive KCl cotransporter 3 Antibody Gaxp Antibody K-Cl cotransporter 3 Antibody KCC 3 Antibody KCC 3A Antibody KCC 3B Antibody KCC3 Antibody KCC3 A Antibody KCC3 B Antibody KCC3A Antibody KCC3B Antibody Potassium chloride cotransporter 3 Antibody Potassium chloride cotransporter KCC3a S3 Antibody S12A6_HUMAN Antibody SLC12 A6 Antibody SLC12A 6 Antibody SLC12A6 Antibody Solute carrier family 12 (potassium/chloride transporters), member 6 Antibody Solute carrier family 12 member 6 Antibody Solute carrier family 12, member 6 Antibody
Information:	Target information shown above is from the UniProt Consortium.