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Anti-SIRT3 Antibody

品牌：Antibodies

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規(guī)格：100μg

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Anti-SIRT3 Antibody

商品詳情參考文獻(xiàn) 相關(guān)資料

Overview

Name:	Anti-SIRT3 Antibody See all SIRT3 primary antibodies
Description:	Goat polyclonal antibody to SIRT3.
Applications:	ELISA, WB
Reactivity:	Human
Immunogen:	Synthetic peptide corresponding to Human SIRT3 (C terminal).
Sequence:	C-QRETGKLDGPDK
Host:	Goat
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	100 μg at 0.5 mg/ml.
Product Form:	Liquid
Formulation:	Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

Function:	NAD-dependent protein deacetylase. Activates or deactivates mitochondrial target proteins by deacetylating key lysine residues. Known targets include ACSS1, IDH, GDH, SOD2, PDHA1, LCAD, SDHA and the ATP synthase subunit ATP5O. Contributes to the regulation of the cellular energy metabolism. Important for regulating tissue-specific ATP levels.
Tissue Specificity:	Widely expressed.
Sequence Similarities:	Belongs to the sirtuin family. Class I subfamily.
Post-Translational Modification:	Processed by mitochondrial processing peptidase (MPP) to give a 28 kDa product. Such processing is probably essential for its enzymatic activity.
Cellular Location:	Mitochondrion matrix.
Database Links:	Entrez Gene: 23410?Human Omim: 604481?Human SwissProt: Q9NTG7?Human Unigene: 716456?Human
Synonyms:	hSIRT 3 Antibody hSIRT3 Antibody Mitochondrial nicotinamide adenine dinucleotide dependent deacetylase Antibody NAD dependent deacetylase sirtuin 3 mitochondrial Antibody NAD-dependent protein deacetylase sirtuin-3, mitochondrial Antibody Regulatory protein SIR2 homolog 3 Antibody Silent mating type information regulation 2 S.cerevisiae homolog 3 Antibody Sir 2 like 3 Antibody SIR 2 like protein 3 Antibody SIR 3 Antibody SIR2 L3 Antibody Sir2 like 3 Antibody SIR2 like protein 3 Antibody SIR2-like protein 3 Antibody SIR2L3 Antibody SIR3_HUMAN Antibody SIRT 3 Antibody SIRT3 Antibody Sirtuin 3 Antibody Sirtuin silent mating type information regulation 2 homolog 3 (S. cerevisiae) Antibody Sirtuin type 3 Antibody Sirtuin3 Antibody
Information:	Target information shown above is from the UniProt Consortium.