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Anti-SIRT3 Antibody

品牌：Antibodies

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規(guī)格：50μl

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Anti-SIRT3 Antibody

商品詳情參考文獻(xiàn) 相關(guān)資料

Overview

Name:	Anti-SIRT3 Antibody See all SIRT3 primary antibodies
Description:	Rabbit polyclonal antibody to SIRT3.
Applications:	WB, IHC, IF
Dilutions:	WB: 1:500 - 1:2000, IHC: 1:50 - 1:100, IF: 1:50 - 1:100.
Reactivity:	Human, Mouse, Rat
Immunogen:	A synthetic peptide of human SIRT3.
Protein Length:	399
Host:	Rabbit
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Affinity purification.
Product Form:	Liquid
Formulation:	Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

Function:	NAD-dependent protein deacetylase. Activates or deactivates mitochondrial target proteins by deacetylating key lysine residues. Known targets include ACSS1, IDH, GDH, SOD2, PDHA1, LCAD, SDHA and the ATP synthase subunit ATP5O. Contributes to the regulation of the cellular energy metabolism. Important for regulating tissue-specific ATP levels.
Tissue Specificity:	Widely expressed.
Sequence Similarities:	Belongs to the sirtuin family. Class I subfamily.
Post-Translational Modification:	Processed by mitochondrial processing peptidase (MPP) to give a 28 kDa product. Such processing is probably essential for its enzymatic activity.
Cellular Location:	Mitochondrion matrix.
Database Links:	Entrez Gene: 23410?Human Entrez Gene: 64384?Mouse Entrez Gene: 293615?Rat Omim: 604481?Human SwissProt: Q9NTG7?Human SwissProt: Q8R104?Mouse Unigene: 716456?Human Unigene: 244216?Mouse Unigene: 24698?Rat
Synonyms:	hSIRT 3 Antibody hSIRT3 Antibody Mitochondrial nicotinamide adenine dinucleotide dependent deacetylase Antibody NAD dependent deacetylase sirtuin 3 mitochondrial Antibody NAD-dependent protein deacetylase sirtuin-3, mitochondrial Antibody Regulatory protein SIR2 homolog 3 Antibody Silent mating type information regulation 2 S.cerevisiae homolog 3 Antibody Sir 2 like 3 Antibody SIR 2 like protein 3 Antibody SIR 3 Antibody SIR2 L3 Antibody Sir2 like 3 Antibody SIR2 like protein 3 Antibody SIR2-like protein 3 Antibody SIR2L3 Antibody SIR3_HUMAN Antibody SIRT 3 Antibody SIRT3 Antibody Sirtuin 3 Antibody Sirtuin silent mating type information regulation 2 homolog 3 (S. cerevisiae) Antibody Sirtuin type 3 Antibody Sirtuin3 Antibody
Information:	Target information shown above is from the UniProt Consortium.