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Anti-SGCD Antibody

品牌：Antibodies

貨號：

規(guī)格：50μl

貨期：

應用：

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Anti-SGCD Antibody

商品詳情參考文獻相關資料

Overview

Name:	Anti-SGCD Antibody See all SGCD primary antibodies
Description:	Rabbit polyclonal antibody to SGCD.
Applications:	WB, IHC, IF
Dilutions:	WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:100.
Reactivity:	Human, Mouse, Rat
Immunogen:	Recombinant protein of human SGCD.
Protein Length:	289 (290)
Host:	Rabbit
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Affinity purification.
Product Form:	Liquid
Formulation:	Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

Function:	Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
Tissue Specificity:	Most strongly expressed in skeletal and cardiac muscle. Also detected in smooth muscle. Weak expression in brain and lung.
Involvement in Disease:	Limb-girdle muscular dystrophy 2F: An autosomal recessive degenerative myopathy initially affecting the proximal limb girdle musculature. Muscle from patients shows a complete loss of delta-sarcoglycan as well as of the others components of the sarcoglycan complex. Cardiomyopathy, dilated 1L: A disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.
Sequence Similarities:	Belongs to the sarcoglycan beta/delta/gamma/zeta family.
Post-Translational Modification:	Glycosylated.
Cellular Location:	Cell membrane > Sarcolemma. Cytoplasm > Cytoskeleton.
Database Links:	Entrez Gene: 6444?Human Entrez Gene: 24052?Mouse Omim: 601411?Human SwissProt: Q92629?Human SwissProt: P82347?Mouse Unigene: 387207?Human Unigene: 644733?Human Unigene: 338890?Mouse
Synonyms:	35 kDa dystrophin associated glycoprotein Antibody 35 kDa dystrophin-associated glycoprotein Antibody 35DAG Antibody CMD1L Antibody DAGD Antibody delta Sarcoglycan Antibody Delta-sarcoglycan Antibody Delta-SG Antibody Dystrophin associated glycoprotein delta sarcoglycan Antibody LGMD2F Antibody MGC22567 Antibody Placental delta sarcoglycan Antibody Sarcoglycan delta (35 kDa dystrophin associated glycoprotein) Antibody SG delta Antibody SGCD Antibody SGCDP Antibody SGCD_HUMAN Antibody SGD Antibody
Information:	Target information shown above is from the UniProt Consortium.