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Anti-SCO2 Antibody

品牌：Antibodies

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規(guī)格：50μl

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Anti-SCO2 Antibody

商品詳情參考文獻(xiàn) 相關(guān)資料

Overview

Name:	Anti-SCO2 Antibody See all SCO2 primary antibodies
Description:	Rabbit polyclonal antibody to SCO2.
Applications:	WB, IHC
Dilutions:	WB: 1:500 - 1:2000, IHC: 1:50 - 1:200.
Reactivity:	Human, Mouse, Rat
Immunogen:	Recombinant protein of human SCO2.
Protein Length:	266
Host:	Rabbit
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Affinity purification.
Product Form:	Liquid
Formulation:	Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

Function:	Acts as a copper chaperone, transporting copper to the Cu(A) site on the cytochrome c oxidase subunit II (COX2).
Tissue Specificity:	Ubiquitous.
Involvement in Disease:	Cardioencephalomyopathy, fatal infantile, due to cytochrome c oxidase deficiency 1: A disorder characterized by hypotonia, developmental delay, hypertrophic cardiomyopathy, lactic acidosis, gliosis, neuronal loss in basal ganglia, brainstem and spinal cord, and cytochrome c oxidase deficiency. Myopia 6: A refractive error of the eye, in which parallel rays from a distant object come to focus in front of the retina, vision being better for near objects than for far. Leigh syndrome: An early-onset progressive neurodegenerative disorder characterized by the presence of focal, bilateral lesions in one or more areas of the central nervous system including the brainstem, thalamus, basal ganglia, cerebellum and spinal cord. Clinical features depend on which areas of the central nervous system are involved and include subacute onset of psychomotor retardation, hypotonia, ataxia, weakness, vision loss, eye movement abnormalities, seizures, and dysphagia.
Sequence Similarities:	Belongs to the SCO1/2 family.
Cellular Location:	Mitochondrion.
Database Links:	Entrez Gene: 9997?Human Omim: 604272?Human SwissProt: O43819?Human Unigene: 180903?Human Unigene: 592212?Human
Synonyms:	Cytochrome oxidase deficient homolog 2 Antibody MGC125823 Antibody MGC125825 Antibody OTTHUMP00000196774 Antibody OTTHUMP00000196775 Antibody Protein SCO2 homolog, mitochondrial Antibody SCO (cytochrome oxidase deficient, yeast) homolog 2 Antibody SCO 1L Antibody SCO 2 Antibody SCO cytochrome oxidase deficient homolog 2 Antibody SCO cytochrome oxidase deficient homolog 2 (yeast) Antibody SCO1L Antibody SCO2 Antibody SCO2_HUMAN Antibody Synthesis of cytochrome c oxidase 2 Antibody
Information:	Target information shown above is from the UniProt Consortium.