WNT2 pAb detects endogenous levels of WNT2 protein.
Applications:
WB, IHC
Reactivity:
Human, Mouse
Immunogen:
Recombinant full length Human WNT2.
Host:
Rabbit
Clonality:
Polyclonal
Conjugate:
Unconjugated
Molecular Weight:
~ 34, 40 kDa
Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form:
1mg/ml in PBS?with?0.1%?Sodium?Azide,?50%?Glycerol.
Target
Function:
Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters.
Tissue Specificity:
Expressed in brain in the thalamus, in fetal and ***** lung and in placenta.
Sequence Similarities:
Belongs to the Wnt family.
Post-Translational Modification:
Palmitoleylation is required for efficient binding to frizzled receptors. Depalmitoleylation leads to Wnt signaling pathway inhibition.
Cellular Location:
Secreted > Extracellular space > Extracellular matrix.
Database Links:
Entrez Gene: 7472?Human
Entrez Gene: 22413?Mouse
Omim: 147870?Human
SwissProt: P09544?Human
SwissProt: P21552?Mouse
Unigene: 567356?Human
Unigene: 33653?Mouse
Synonyms:
Int 1 related protein Antibody
Int-1-like protein 1 Antibody
Int-1-related protein Antibody
INT1L 1 Antibody
INT1L1 Antibody
IRP Antibody
IRP protein Antibody
ONCOGENE INT1 LIKE 1 Antibody
Protein Wnt-2 Antibody
Secreted growth factor Antibody
Wingless type MMTV integration site family member 2 Antibody
WNT 2 Antibody
Wnt2 Antibody
WNT2_HUMAN Antibody
Information:
Target information shown above is from the UniProt Consortium.