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Anti-WISP1 Antibody

品牌：Antibodies

貨號：

規(guī)格：50μl

貨期：

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Anti-WISP1 Antibody

商品詳情參考文獻相關資料

Overview

Name:	Anti-WISP1 Antibody See all WISP1 primary antibodies
Description:	Rabbit polyclonal antibody to WISP1.
Applications:	WB
Dilutions:	WB: 1:500 - 1:2000.
Reactivity:	Human, Mouse
Immunogen:	Recombinant protein of human WISP1.
Protein Length:	367
Host:	Rabbit
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Affinity purification.
Product Form:	Liquid
Formulation:	Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

Function:	Downstream regulator in the Wnt/Frizzled-signaling pathway. Associated with cell survival. Attenuates p53-mediated apoptosis in response to DNA damage through activation of AKT kinase. Up-regulates the anti-apoptotic Bcl-X(L) protein. Adheres to skin and melanoma fibroblasts. In vitro binding to skin fibroblasts occurs through the proteoglycans, decorin and biglycan.
Tissue Specificity:	Expressed in heart, kidney, lung, pancreas, placenta, ovary, small intestine and spleen. Isoform 2 is expressed predominantly in scirrhous gastric carcinoma and, weakly in placenta. Overexpression is associated with several cancers including breast cancer and colon tumors. Isoform 2 is overexpressed in scirrhous gastric carcinoma.
Sequence Similarities:	Belongs to the CCN family.
Cellular Location:	Secreted.
Database Links:	Entrez Gene: 8840?Human Entrez Gene: 22402?Mouse Omim: 603398?Human SwissProt: O95388?Human SwissProt: O54775?Mouse Unigene: 492974?Human Unigene: 10222?Mouse
Synonyms:	CCN 4 Antibody CCN family member 4 Antibody CCN4 Antibody WISP 1 Antibody WISP 1c Antibody WISP 1i Antibody WISP 1tc Antibody WISP1 Antibody WISP1c Antibody WISP1i Antibody WISP1tc Antibody Wnt 1 induced secreted protein Antibody WNT 1 induced secreted protein 1 Antibody WNT 1 inducible signaling pathway protein 1 Antibody Wnt 1 signaling pathway protein 1 Antibody Wnt-1 inducible signaling pathway protein 1 Antibody Wnt1 induced secreted protein Antibody WNT1 induced secreted protein 1 Antibody WNT1 inducible signaling pathway protein 1 Antibody Wnt1 signaling pathway protein 1 Antibody WNT1-inducible-signaling pathway protein 1 Antibody
Information:	Target information shown above is from the UniProt Consortium.