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Anti-WDR5 Antibody

品牌：Antibodies

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規(guī)格：100μl

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Anti-WDR5 Antibody

商品詳情參考文獻相關資料

Name:	Anti-WDR5 Antibody See all WDR5 primary antibodies
Description:	Rabbit polyclonal antibody to WDR5
Specificity:	WDR5 antibody is human specific. WDR5 antibody is predicted to not cross-react with other WDR family members.
Applications:	E, WB
Reactivity:	Human
Immunogen:	19 amino acid peptide near the amino terminus of human WDR5.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Affinity chromatography purified via peptide column
Formulation:	PBS containing 0.02% sodium azide.
Storage:	Store at 4?C for three months and -20?C, stable for up to one year.

Function:	Contributes to histone modification. May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation.
Sequence Similarities:	Belongs to the WD repeat WDR5/wds family.
Cellular Location:	Nucleus.
Database Links:	Entrez Gene: 11091?Human Omim: 609012?Human SwissProt: P61964?Human Unigene: 397638?Human
Synonyms:	2410008O07Rik Antibody AA408785 Antibody AA960360 Antibody Big Antibody BIG 3 Antibody BIG3 Antibody BMP2 induced 3 kb gene protein Antibody BMP2 induced gene, 3-KB Antibody BMP2-induced 3-kb gene protein Antibody MGC114572 Antibody OTTHUMP00000162494 Antibody SWD 3 Antibody SWD3 Antibody SWD3 Set1c WD40 repeat protein homolog Antibody WD repeat containing protein 5 Antibody WD repeat domain 5 Antibody WD repeat protein 5 Antibody WD repeat-containing protein 5 Antibody WD repeat-containing protein BIG-3 Antibody WDR 5 Antibody WDR5 Antibody WDR5_HUMAN Antibody
Information:	Target information shown above is from the UniProt Consortium.