丁香五月天网,天天日天天射天天色

您好，歡迎來到拜力生物網站！請登錄注冊

我的訂單 | 聯(lián)系我們 | 在線客服QQ：3012681483 | 客服電話：400-968-7988 | 工作時間：08:30-17:30

主營產品： ELISA試劑盒、抗體、補體血清、兔補體、干擾素、小鼠測溫儀、進口試劑、Quidel代理、Swant代理、PBL Assay Science代理

網站首頁產品中心代理品牌新聞資訊資源中心關于我們

所在位置：首頁 > 產品中心 > Antibodies > Antibodies產品

訂購信息

上海拜力生物科技公司

Tel:400-968-7988 021-33779008

Anti-WASP Antibody

品牌：Antibodies

貨號：

規(guī)格：50μl

貨期：

應用：

咨詢客服

立即購買加入購物車

Anti-WASP Antibody

商品詳情參考文獻相關資料

Overview

Name:	Anti-WASP Antibody See all WASP primary antibodies
Description:	Rabbit polyclonal antibody to WASP
Specificity:	The antibody detects endogenous level of total WASP protein.
Applications:	WB
Reactivity:	Human, Mouse, Rat
Immunogen:	Peptide sequence around aa.289~293 (L-I-Y-D-F) derived from Human WASP.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Concentration:	1.0mg / ml
Formulation:	Supplied at 1.0mg / mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage:	Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target

Function:	Effector protein for Rho-type GTPases. Regulates actin filament reorganization via its interaction with the Arp2/3 complex. Important for efficient actin polymerization. Possible regulator of lymphocyte and platelet function. Mediates actin filament reorganization and the formation of actin pedestals upon infection by pathogenic bacteria.
Tissue Specificity:	Expressed predominantly in the thymus. Also found, to a much lesser extent, in the spleen.
Involvement in Disease:	Wiskott-Aldrich syndrome: An X-linked recessive immunodeficiency characterized by eczema, thrombocytopenia, recurrent infections, and bloody diarrhea. Death usually occurs before age 10. Thrombocytopenia 1: Thrombocytopenia is defined by a decrease in the number of platelets in circulating blood, resulting in the potential for increased bleeding and decreased ability for clotting. Neutropenia, severe congenital, X-linked: A disorder of hematopoiesis characterized by maturation arrest of granulopoiesis at the level of promyelocytes with peripheral blood absolute neutrophil counts below 0.5 x 10(9)/l and early onset of severe bacterial infections.
Post-Translational Modification:	Phosphorylated at Tyr-291 by FYN and HCK, inducing WAS effector activity after TCR engagement. Phosphorylation at Tyr-291 enhances WAS activity in promoting actin polymerization and filopodia formation.
Cellular Location:	Cytoplasm > Cytoskeleton.
Database Links:	Entrez Gene: 7454?Human Entrez Gene: 22376?Mouse Entrez Gene: 317371?Rat Omim: 300392?Human SwissProt: P42768?Human SwissProt: P70315?Mouse Unigene: 2157?Human Unigene: 4735?Mouse
Synonyms:	Eczema thrombocytopenia Antibody IMD2 Antibody SCNX Antibody THC Antibody THC1 Antibody Thrombocytopenia 1 (X linked) Antibody U42471 Antibody Was Antibody WASP Antibody WASP_HUMAN Antibody Wiskott Aldrich syndrome Antibody Wiskott Aldrich syndrome (eczema thrombocytopenia) Antibody Wiskott Aldrich syndrome protein Antibody Wiskott-Aldrich syndrome protein Antibody
Information:	Target information shown above is from the UniProt Consortium.