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Anti-Hexim1 Antibody

品牌：Antibodies

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規(guī)格：50μl

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Anti-Hexim1 Antibody

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Overview

Name:	Anti-Hexim1 Antibody See all Hexim1 primary antibodies
Description:	Rabbit polyclonal antibody to Hexim1
Specificity:	Hexim1 Polyclonal Antibody detects endogenous levels of Hexim1 protein.
Applications:	WB, IHC, IF, ELISA
Reactivity:	Human, Mouse, Rat
Immunogen:	Synthesized peptide derived from the Internal region of human Hexim1.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1mg / ml
Formulation:	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage:	Store at -20?C / 1 year

Target

Function:	Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. May also regulate NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity.
Tissue Specificity:	Ubiquitously expressed with higher expression in placenta. HEXIM1 and HEXIM2 are differentially expressed. Expressed in endocrine tissues.
Sequence Similarities:	Belongs to the HEXIM family.
Cellular Location:	Nucleus. Cytoplasm. Binds alpha-importin and is mostly nuclear (PubMed:16362050).
Database Links:	Entrez Gene: 10614?Human Entrez Gene: 192231?Mouse Entrez Gene: 498008?Rat Omim: 607328?Human SwissProt: O94992?Human SwissProt: Q8R409?Mouse SwissProt: Q5M9G1?Rat Unigene: 15299?Human Unigene: 586945?Human Unigene: 634944?Human Unigene: 741758?Human Unigene: 8763?Mouse Unigene: 113703?Rat
Synonyms:	Cardiac lineage protein 1 Antibody CLP 1 Antibody CLP1 Antibody EDG 1 Antibody EDG1 Antibody Estrogen down-regulated gene 1 protein Antibody FLJ13562 Antibody Hexamethylene bis acetamide inducible 1 Antibody Hexamethylene bis acetamide inducible protein Antibody Hexamethylene bis acetamide inducible transcript 1 Antibody Hexamethylene bis-acetamide-inducible protein 1 Antibody HEXI1_HUMAN Antibody HEXIM 1 Antibody HEXIM1 Antibody HEXIM1 protein Antibody HIS 1 Antibody HIS1 Antibody HMBA inducible Antibody MAQ 1 Antibody MAQ1 Antibody Menage a quatre 1 Antibody Menage a quatre protein 1 Antibody Protein HEXIM1 Antibody
Information:	Target information shown above is from the UniProt Consortium.