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Anti-HES1 Antibody

品牌：Antibodies

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規(guī)格：100μl

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Anti-HES1 Antibody

商品詳情參考文獻(xiàn) 相關(guān)資料

Name:	Anti-HES1 Antibody See all HES1 primary antibodies
Description:	Rabbit polyclonal antibody to HES1
Specificity:	The antibody detects endogenous levels of total HES1 protein.
Applications:	IHC
Reactivity:	Human
Immunogen:	Synthetic peptide of human HES1
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Antigen affinity purification
Concentration:	0.5mg / ml
Formulation:	Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Storage:	Store at -20?C

Function:	Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity (By similarity). May play a role in a functional FA core complex response to DNA cross-link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage.
Cellular Location:	Nucleus.
Database Links:	Entrez Gene: 3280?Human Omim: 139605?Human SwissProt: Q14469?Human Unigene: 250666?Human
Synonyms:	bHLHb39 Antibody C-HAIRY1 Antibody c-hairy1A Antibody Class B basic helix-loop-helix protein 39 Antibody FLJ20408 Antibody Hairy and enhancer of split 1 Antibody Hairy and enhancer of split 1 (Drosophila) Antibody Hairy homolog Antibody Hairy homolog (Drosophila) Antibody Hairy like Antibody Hairy, Drosophila, homolog of Antibody Hairy-like protein Antibody Hairy/enhancer of split, Drosophila, homolog of, 1 Antibody HAIRY1 Antibody HES-1 Antibody Hes1 Antibody Hes1 hairy and enhancer of split 1 (Drosophila) Antibody HES1_HUMAN Antibody HHL Antibody HL Antibody HRY Antibody MGC129109 Antibody OTTHUMP00000209031 Antibody RHL Antibody Transcription factor HES-1 Antibody
Information:	Target information shown above is from the UniProt Consortium.