Hamster monoclonal (22F6) antibody to Helios (PE).
Specificity:
The armenian hamster monoclonal antibody 22F6 recognizes Helios, a transcription factor expressed in some hematopoietic stem cells, and at high levels in thymic-derived regulatory T cells.
Applications:
FC
Reactivity:
Human, Mouse
Immunogen:
Peptide coresponding to the amino acids 51-107 of Helios.
Host:
Hamster
Clonality:
Monoclonal
Clone:
22F6
Isotype:
IgG
Conjugate:
PE
Purification:
Size exclusion chromatography.
Product Form:
Liquid
Formulation:
Supplied in Phosphate Buffered Saline with 15mM Sodium Azide.
Storage:
Store in the dark at 2-8°C. Avoid prolonged exposure to light.
Target
Function:
Associates with Ikaros at centromeric heterochromatin.
Tissue Specificity:
Restricted to the T-cell lineage. Abundant in thymus, low expression in bone marrow and brain and no detectable expression in spleen, liver, kidney or muscle.
Sequence Similarities:
Belongs to the Ikaros C2H2-type zinc-finger protein family.
Cellular Location:
Nucleus.
Database Links:
Entrez Gene: 22807?Human
Entrez Gene: 22779?Mouse
Omim: 606234?Human
SwissProt: Q9UKS7?Human
SwissProt: P81183?Mouse
Unigene: 604950?Human
Unigene: 106343?Mouse
Synonyms:
ANF1A2 Antibody
HELIOS Antibody
IKAROS family zinc finger 2 Antibody
Ikaros family zinc finger protein 2 Antibody
IKZF 2 Antibody
IKZF2 Antibody
IKZF2_HUMAN Antibody
MGC34330 Antibody
Zinc finger DNA binding protein Helios Antibody
Zinc finger protein Helios Antibody
Zinc finger protein subfamily 1A 2 Antibody
ZNF1A2 Antibody
ZNFN1A2 Antibody
Information:
Target information shown above is from the UniProt Consortium.