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Anti-Serine / threonine-protein phosphatase 2A catalytic subunit beta isoform A

品牌：Antibodies

貨號：

規(guī)格：100μl

貨期：

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Anti-Serine / threonine-protein phosphatase 2A catalytic subunit beta isoform Antibody

商品詳情參考文獻(xiàn) 相關(guān)資料

Name:	Anti-Serine / threonine-protein phosphatase 2A catalytic subunit beta isoform Antibody See all Serine primary antibodies
Description:	Rabbit polyclonal antibody to Serine / threonine-protein phosphatase 2A catalytic subunit beta isoform
Specificity:	The antibody detects endogenous level of total Serine / threonine-protein phosphatase 2A catalytic subunit beta isoform polyclonal antibody.
Applications:	WB, IHC
Reactivity:	Human
Immunogen:	Recombinant human Serine / threonine-protein phosphatase 2A catalytic subunit beta isoform protein
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Caprylic Acid Ammonium Sulfate Precipitation purified
Concentration:	1.0mg / mL
Formulation:	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Storage:	Store at -20?C

Function:	PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase.
Sequence Similarities:	Belongs to the PPP phosphatase family. PP-1 subfamily.
Post-Translational Modification:	Reversibly methyl esterified on Leu-309 by leucine carboxyl methyltransferase 1 (LCMT1) and protein phosphatase methylesterase 1 (PPME1). Carboxyl methylation influences the affinity of the catalytic subunit for the different regulatory subunits, thereby modulating the PP2A holoenzyme's substrate specificity, enzyme activity and cellular localization.
Cellular Location:	Cytoplasm. Nucleus. Chromosome > Centromere. Cytoplasm > Cytoskeleton > Spindle pole. In prometaphase cells, but not in anaphase cells, localizes at centromeres. During mitosis, also found at spindle poles.