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Anti-SELPLG Antibody

品牌：Antibodies

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規(guī)格：100μl

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Anti-SELPLG Antibody

商品詳情參考文獻(xiàn) 相關(guān)資料

Overview

Name:	Anti-SELPLG Antibody See all SELPLG primary antibodies
Description:	Rabbit polyclonal antibody to SELPLG
Specificity:	The antibody detects endogenous level of total SELPLG protein.
Applications:	WB, IHC, IF
Reactivity:	Human
Immunogen:	Recombinant protein of human SELPLG.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Antibodies were purified by affinity purification using immunogen.
Concentration:	1.0mg / ml
Formulation:	Supplied at 1.0mg / mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage:	Store at -20?C

Target

Function:	A SLe(x)-type proteoglycan, which through high affinity, calcium-dependent interactions with E-, P- and L-selectins, mediates rapid rolling of leukocytes over vascular surfaces during the initial steps in inflammation. Critical for the initial leukocyte capture.
Tissue Specificity:	Expressed on neutrophils, monocytes and most lymphocytes.
Post-Translational Modification:	Displays complex, core-2, sialylated and fucosylated O-linked oligosaccharides, at least some of which appear to contain poly-N-acetyllactosamine with varying degrees of substitution. Mainly disialylated or neutral forms of the core-2 tetrasaccharide, Galbeta1-->4GlcNAcbeta1-->6(Galbeta1-->3)GalNAcOH. The GlcN:GalN ratio is approximately 2:1 and the Man:Fuc ratio 3:5. Contains about 14% fucose with alpha-1,3 linkage present in two forms: One species is a disialylated, monofucosylated glycan, and the other, a monosialylated, trifucosylated glycan with a polylactosamine backbone. The fucosylated forms carry the Lewis antigen and are important for interaction with selectins and for functioning in leukocyte rolling. The modification containing the sialyl Lewis X glycan is on Thr-57. No sulfated O-glycans. Some N-glycosylation.
Cellular Location:	Membrane.
Database Links:	Entrez Gene: 6404?Human Omim: 600738?Human SwissProt: Q14242?Human Unigene: 591014?Human
Synonyms:	CD 162 Antibody CD162 Antibody CD162 antigen Antibody CLA Antibody Cutaneous lymphocyte associated associated antigen Antibody P selectin glycoprotein ligand 1 Antibody P selectin glycoprotein ligand 1 precursor Antibody P-selectin glycoprotein ligand 1 Antibody PSGL 1 Antibody PSGL-1 Antibody PSGL1 Antibody Selectin P ligand Antibody SELPLG Antibody SELPL_HUMAN Antibody
Information:	Target information shown above is from the UniProt Consortium.