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Anti-Rhodopsin (L328) Antibody

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規(guī)格：50μl

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Anti-Rhodopsin (L328) Antibody

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Overview

Name:	Anti-Rhodopsin (L328) Antibody See all Rhodopsin primary antibodies
Description:	Rabbit polyclonal antibody to Rhodopsin (L328)
Specificity:	Rhodopsin (L328) pAb detects endogenous levels of Rhodopsin protein.
Applications:	WB, IHC
Reactivity:	Human, Mouse, Rat
Immunogen:	Synthetic peptide, corresponding to amino acids 301-350 of Human Rhodopsin.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Molecular Weight:	~ 42 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form:	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Target

Function:	Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change leading to G-protein activation and release of all-trans retinal.
Tissue Specificity:	Rod shaped photoreceptor cells which mediates vision in dim light.
Involvement in Disease:	Retinitis pigmentosa 4: A retinal dystrophy belonging to the group of pigmentary retinopathies. Retinitis pigmentosa is characterized by retinal pigment deposits visible on fundus examination and primary loss of rod photoreceptor cells followed by secondary loss of cone photoreceptors. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. Night blindness, congenital stationary, autosomal dominant 1: A non-progressive retinal disorder characterized by impaired night vision, often associated with nystagmus and myopia.
Sequence Similarities:	Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
Post-Translational Modification:	Phosphorylated on some or all of the serine and threonine residues present in the C-terminal region.
Cellular Location:	Membrane. Synthesized in the inner segment (IS) of rod photoreceptor cells before vectorial transport to the rod outer segment (OS) photosensory cilia.
Database Links:	Entrez Gene: 6010?Human Entrez Gene: 212541?Mouse Entrez Gene: 24717?Rat Omim: 180380?Human SwissProt: P08100?Human SwissProt: P15409?Mouse SwissProt: P51489?Rat Unigene: 247565?Human Unigene: 2965?Mouse Unigene: 406156?Mouse Unigene: 92530?Rat
Synonyms:	CSNBAD1 Antibody MGC138309 Antibody MGC138311 Antibody OPN 2 Antibody OPN2 Antibody opsd Antibody OPSD_HUMAN Antibody opsin 2 Antibody Opsin 2 rod pigment Antibody Opsin-2 Antibody Opsin2 Antibody Retinitis Pigmentosa 4 Antibody Retinitis pigmentosa 4 autosomal dominant Antibody RHO Antibody Rhodopsin Antibody RP 4 Antibody RP4 Antibody
Information:	Target information shown above is from the UniProt Consortium.