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Anti-RDH5 Antibody

品牌：Antibodies

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規(guī)格：100μg

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Anti-RDH5 Antibody

商品詳情參考文獻(xiàn) 相關(guān)資料

Overview

Name:	Anti-RDH5 Antibody See all RDH5 primary antibodies
Description:	Goat polyclonal antibody to RDH5.
Applications:	ELISA, WB, IHC
Reactivity:	Human, Mouse
Immunogen:	Synthetic peptide corresponding to Human RDH5 (internal region).
Sequence:	C-RDRQSLPASNAFV
Host:	Goat
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	100 μg at 0.5 mg/ml.
Product Form:	Liquid
Formulation:	Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

Function:	Stereospecific 11-cis retinol dehydrogenase, which catalyzes the final step in the biosynthesis of 11-cis retinaldehyde, the universal chromophore of visual pigments. Also able to oxidize 9-cis-retinol and 13-cis-retinol, but not all-trans-retinol. Active in the presence of NAD as cofactor but not in the presence of NADP.
Tissue Specificity:	Expressed in eye, liver, kidney, brain, intestine, placenta, epididymus and submaxillary gland. In eye, strongly expressed in the retinal pigment epithelium, with lower expression levels detected in the inner segment of the photoreceptor cells and in the outer plexiform layer. In kidney, strong expression detected in the distal tubules and the transitional epithelium in the renal pelvis, with weaker expression detected in the epithelium of the outer stripe of the outer zone of the medulla. In liver, detected in hepatocytes in the centrilobular area. In lung, present in Clara cells in the epithelium of the bronchiole, in parenchyma and in cartilage surrounding the secondary bronchi. In skin, expressed in epidermis, hair follicles and mast cells in the dermis. Expressed in heart (PubMed:10588954 and PubMed:10739682). Not detected in heart (PubMed:9539749). Not detected in lung, spleen, skeletal muscle and testis.
Sequence Similarities:	Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Cellular Location:	Membrane. Endoplasmic reticulum lumen.
Database Links:	Entrez Gene: 5959?Human Entrez Gene: 19682?Mouse Omim: 601617?Human SwissProt: Q92781?Human SwissProt: O55240?Mouse
Synonyms:	11 cis RDH Antibody 11 cis retinol dehydrogenase Antibody 9 cis retinol specific dehydrogenase Antibody FLJ39337 Antibody FLJ97089 Antibody HSD17B9 Antibody RDH 5 Antibody RDH1 Antibody RDH5 Antibody Retinol dehydrogenase 1 Antibody Retinol dehydrogenase 5 Antibody Retinol dehydrogenase 5 (11 cis/9 cis) Antibody SDR9C5 Antibody Short chain dehydrogenase/reductase family 9C member 5 Antibody
Information:	Target information shown above is from the UniProt Consortium.