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Anti-RASSF7 Antibody

品牌：Antibodies

貨號(hào)：

規(guī)格：100μl

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Anti-RASSF7 Antibody

商品詳情參考文獻(xiàn) 相關(guān)資料

Name:	Anti-RASSF7 Antibody See all RASSF7 primary antibodies
Description:	Rabbit polyclonal antibody to RASSF7
Specificity:	The antibody detects endogenous levels of total RASSF7 protein.
Applications:	WB, IHC
Reactivity:	Human
Immunogen:	Fusion protein corresponding to residues near the C terminal of human Ras association (RalGDS / AF-6) domain family (N-terminal) member 7
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Antigen affinity purification.
Concentration:	1.6mg / ml
Formulation:	Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Storage:	Store at -20?C

Function:	Negatively regulates stress-induced JNK activation and apoptosis by promoting MAP2K7 phosphorylation and inhibiting its ability to activate JNK. Following prolonged stress, anti-apoptotic effect stops because of degradation of RASSF7 protein via the ubiquitin-proteasome pathway. Required for the activation of AURKB and chromosomal congression during mitosis where it stimulates microtubule polymerization.
Post-Translational Modification:	Polyubiquitinated and degraded by the proteasome upon prolonged stress stimuli.
Cellular Location:	Cytoplasm > Cytoskeleton > Microtubule organizing center > Centrosome. Colocalizes with gamma-tubulin.
Database Links:	Entrez Gene: 8045?Human Omim: 143023?Human SwissProt: Q02833?Human Unigene: 72925?Human
Synonyms:	C11orf13 Antibody Chromosome 11 open reading frame 13 Antibody HRAS1 Antibody HRAS1 related cluster 1 Antibody HRAS1 related cluster protein 1 Antibody HRAS1-related cluster protein 1 Antibody HRC1 Antibody MGC126069 Antibody MGC126070 Antibody Ras association (RalGDS/AF 6) domain family (N terminal) member 7 Antibody Ras association (RalGDS/AF 6) domain family 7 Antibody Ras association domain containing protein 7 Antibody Ras association domain-containing protein 7 Antibody RASF7_HUMAN Antibody RASSF 7 Antibody RASSF7 Antibody
Information:	Target information shown above is from the UniProt Consortium.