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Anti-Rad23B (5H1) Antibody

品牌：Antibodies

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規(guī)格：50μl

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Anti-Rad23B (5H1) Antibody

商品詳情參考文獻(xiàn) 相關(guān)資料

Overview

Name:	Anti-Rad23B (5H1) Antibody See all Rad23B primary antibodies
Description:	Mouse monoclonal antibody to Rad23B (5H1)
Specificity:	This antibody detects endogenous levels of Rad23B and does not cross-react with related proteins.
Applications:	WB, ICC, IHC
Reactivity:	Human, Mouse, Rat, Monkey
Immunogen:	Purified recombinant human Rad23B protein fragments expressed in E.coli.
Host:	Mouse
Clonality:	Monoclonal
Conjugate:	Unconjugated
Molecular Weight:	Predicted band size:55KDa Observed band size:55KDa
Purity:	The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form:	Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol

Target

Function:	Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome. May play a role in endoplasmic reticulum-associated degradation (ERAD) of misfolded glycoproteins by association with PNGase and delivering deglycosylated proteins to the proteasome.
Sequence Similarities:	Belongs to the RAD23 family.
Cellular Location:	Nucleus. Cytoplasm. The intracellular distribution is cell cycle dependent. Localized to the nucleus and the cytoplasm during G1 phase. Nuclear levels decrease during S-phase; upon entering mitosis, relocalizes in the cytoplasm without association with chromatin.
Database Links:	Entrez Gene: 5887?Human Entrez Gene: 19359?Mouse Entrez Gene: 298012?Rat Omim: 600062?Human SwissProt: P54727?Human SwissProt: P54728?Mouse SwissProt: Q4KMA2?Rat Unigene: 521640?Human Unigene: 196846?Mouse Unigene: 67042?Rat
Synonyms:	hHR 23b Antibody hHR23b Antibody HR 23B Antibody HR23B Antibody mHR 23B Antibody mHR23B Antibody p58 Antibody RAD 23B Antibody RAD23 (S. cerevisiae) homolog B Antibody RAD23 homolog B Antibody RAD23 homolog B (S. cerevisiae) Antibody RAD23 yeast homolog of B Antibody Rad23b Antibody RD23B_HUMAN Antibody UV excision repair protein RAD23 homolog B Antibody XP C repair complementing complex 58 kDa Antibody XP C repair complementing complex 58 kDa protein Antibody XP C repair complementing protein Antibody XP-C repair-complementing complex 58 kDa protein Antibody XPC repair complementing complex 58 kDa Antibody XPC repair complementing complex 58 kDa protein Antibody XPC repair complementing protein Antibody
Information:	Target information shown above is from the UniProt Consortium.