Actinin-α3 (E25) pAb detects endogenous levels of actinin-α3 protein, this antibody does not cross-react with other α-actinin isoforms.
Applications:
WB, IF
Reactivity:
Human, Mouse, Rat
Immunogen:
Synthetic peptide, corresponding to the N-terminus of Human Actinin-α3.
Host:
Rabbit
Clonality:
Polyclonal
Conjugate:
Unconjugated
Molecular Weight:
~ 103 kDa
Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form:
1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
Target
Function:
F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.
Tissue Specificity:
Expressed only in a subset of type 2 skeletal muscle fibers.