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Anti-TPPP Antibody

品牌：Antibodies

貨號：

規(guī)格：100μg

貨期：

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Anti-TPPP Antibody

商品詳情參考文獻相關資料

Name:	Anti-TPPP Antibody See all TPPP primary antibodies
Description:	Goat polyclonal antibody to TPPP.
Applications:	ELISA, WB, IHC
Reactivity:	Human, Mouse, Rat
Immunogen:	Synthetic peptide corresponding to Human TPPP (internal region).
Sequence:	C-DPSKDRAAKRLSLES
Host:	Goat
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	100 μg at 0.5 mg/ml.
Product Form:	Liquid
Formulation:	Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Function:	May play a role in the polymerization of tubulin into microtubules, microtubule bundling and the stabilization of existing microtubules, thus maintaining the integrity of the microtubule network. May play a role in mitotic spindle assembly and nuclear envelope breakdown.
Tissue Specificity:	Widely expressed with higher expression in brain (at protein level).
Sequence Similarities:	Belongs to the TPPP family.
Post-Translational Modification:	Poor substrate for GSK3. Phosphorylated by LIMK1 on serine residues. Phosphorylation may alter the tubulin polymerization activity.
Cellular Location:	Cytoplasm. Cytoplasm > Cytoskeleton. Nucleus.
Database Links:	Entrez Gene: 11076?Human Entrez Gene: 72948?Mouse Entrez Gene: 361466?Rat Omim: 608773?Human SwissProt: O94811?Human SwissProt: Q7TQD2?Mouse Unigene: 481466?Human Unigene: 39752?Mouse
Synonyms:	25 kDa brain specific protein Antibody 25 kDa brain-specific protein Antibody Brain specific protein p25 alpha Antibody Glycogen synthase kinase 3 (GSK3) inhibitor p24 Antibody OTTHUMP00000161630 Antibody p24 Antibody p25 Antibody p25-alpha Antibody p25alpha Antibody TPPP Antibody TPPP/p25 Antibody TPPP1 Antibody TPPP_HUMAN Antibody Tubulin Polymerization Promoting Protein Antibody Tubulin polymerization-promoting protein Antibody
Information:	Target information shown above is from the UniProt Consortium.