Synthetic peptide corresponding to Human NRAS (internal region).
Sequence:
C-RMKKLNSSDDGTQ
Host:
Goat
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Unconjugated
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:
100 μg at 0.5 mg/ml.
Product Form:
Liquid
Formulation:
Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage:
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Target
Function:
Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.
Sequence Similarities:
Belongs to the small GTPase superfamily. Ras family.
Post-Translational Modification:
Palmitoylated by the ZDHHC9-GOLGA7 complex. Depalmitoylated by ABHD17A, ABHD17B and ABHD17C. A continuous cycle of de- and re-palmitoylation regulates rapid exchange between plasma membrane and Golgi.
Cellular Location:
Cell membrane. Golgi apparatus membrane.
Shuttles between the plasma membrane and the Golgi apparatus.
Database Links:
Entrez Gene: 4893?Human
Entrez Gene: 24605?Rat
Omim: 164790?Human
SwissProt: P01111?Human
SwissProt: Q04970?Rat
Unigene: 486502?Human
Unigene: 217722?Rat
Synonyms:
ALPS4 Antibody
AV095280 Antibody
GTPase NRas Antibody
HRAS1 Antibody
N ras Antibody
N ras protein part 4 Antibody
Neuroblastoma RAS viral (v ras) oncogene homolog Antibody
NRAS Antibody
NRAS1 Antibody
NS6 Antibody
OTTHUMP00000013879 Antibody
OTTMUSP00000023521 Antibody
RASN_HUMAN Antibody
Transforming protein N Ras Antibody
Transforming protein N-Ras Antibody
v ras neuroblastoma RAS viral oncogene homolog Antibody
Information:
Target information shown above is from the UniProt Consortium.