大香蕉五月丁香花超碰网,无码中文欧美一区二区三,亚洲激情婷婷日

您好，歡迎來到拜力生物網(wǎng)站！請登錄注冊

我的訂單 | 聯(lián)系我們 | 在線客服QQ：3012681483 | 客服電話：400-968-7988 | 工作時間：08:30-17:30

主營產(chǎn)品： ELISA試劑盒、抗體、補體血清、兔補體、干擾素、小鼠測溫儀、進口試劑、Quidel代理、Swant代理、PBL Assay Science代理

網(wǎng)站首頁產(chǎn)品中心代理品牌新聞資訊資源中心關(guān)于我們

所在位置：首頁 > 產(chǎn)品中心 > Antibodies > Antibodies產(chǎn)品

訂購信息

上海拜力生物科技公司

Tel:400-968-7988 021-33779008

Anti-MyD88 Antibody

品牌：Antibodies

貨號：

規(guī)格：50μl

貨期：

應用：

咨詢客服

立即購買加入購物車

Anti-MyD88 Antibody

商品詳情參考文獻相關(guān)資料

Overview

Name:	Anti-MyD88 Antibody See all MyD88 primary antibodies
Description:	Rabbit polyclonal antibody to MyD88
Specificity:	MYD88 pAb detects endogenous levels of MYD88 protein.
Applications:	WB, IHC, IF
Reactivity:	Human, Mouse, Rat
Immunogen:	Recombinant full length Human MyD88.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Molecular Weight:	~ 35 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form:	1mg/ml in PBS?with?0.1%?Sodium?Azide,?50%?Glycerol.

Target

Function:	Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes. MyD88-mediated signaling in intestinal epithelial cells is crucial for maintenance of gut homeostasis and controls the expression of the antimicrobial lectin REG3G in the small intestine.
Tissue Specificity:	Ubiquitous.
Involvement in Disease:	MYD88 deficiency: Patients suffer from autosomal recessive, life-threatening, often recurrent pyogenic bacterial infections, including invasive pneumococcal disease, and die between 1 and 11 months of age. Surviving patients are otherwise healthy, with normal resistance to other microbes, and their clinical status improved with age.
Cellular Location:	Cytoplasm.
Database Links:	Entrez Gene: 4615?Human Entrez Gene: 17874?Mouse Entrez Gene: 301059?Rat Omim: 602170?Human SwissProt: Q99836?Human SwissProt: P22366?Mouse SwissProt: Q6Y1S1?Rat Unigene: 82116?Human Unigene: 213003?Mouse Unigene: 37341?Rat
Synonyms:	Mutant myeloid differentiation primary response 88 Antibody MYD 88 Antibody MyD88 Antibody MYD88D Antibody MYD88_HUMAN Antibody Myeloid differentiation marker 88 Antibody Myeloid differentiation primary response 88 Antibody Myeloid differentiation primary response gene Antibody Myeloid differentiation primary response gene (88) Antibody Myeloid differentiation primary response gene 88 Antibody Myeloid differentiation primary response protein MyD88 Antibody OTTHUMP00000161718 Antibody OTTHUMP00000208595 Antibody OTTHUMP00000209058 Antibody OTTHUMP00000209059 Antibody OTTHUMP00000209060 Antibody
Information:	Target information shown above is from the UniProt Consortium.