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Anti-ACVR1C Antibody

品牌：Antibodies

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規(guī)格：50μl

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Anti-ACVR1C Antibody

商品詳情參考文獻(xiàn) 相關(guān)資料

Overview

Name:	Anti-ACVR1C Antibody See all ACVR1C primary antibodies
Description:	Rabbit polyclonal antibody to ACVR1C.
Applications:	WB, IHC
Dilutions:	WB: 1:500 - 1:2000, IHC: 1:100 - 1:200.
Reactivity:	Human, Mouse, Rat
Immunogen:	Recombinant protein of human ACVR1C.
Protein Length:	493
Host:	Rabbit
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Affinity purification.
Product Form:	Liquid
Formulation:	Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

Function:	Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis.
Tissue Specificity:	Present in pancreas, heart, colon, small intestine, ovary and the hippocampus, medulla oblongata and putamen of the brain. Isoform 1, isoform 2, isoform 3 and isoform 4 are all expressed in the placenta throughout pregnancy.
Sequence Similarities:	Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
Cellular Location:	Membrane.
Database Links:	Entrez Gene: 130399?Human Entrez Gene: 269275?Mouse Entrez Gene: 245921?Rat Omim: 608981?Human SwissProt: Q8NER5?Human SwissProt: Q8K348?Mouse SwissProt: P70539?Rat Unigene: 562901?Human Unigene: 77751?Mouse Unigene: 10580?Rat
Synonyms:	Activin A Receptor Type IC Antibody Activin A receptor, type IC Antibody Activin receptor like kinase 7 Antibody Activin receptor type 1C precursor Antibody Activin receptor type IC Antibody Activin receptor type-1C Antibody Activin receptor-like kinase 7 Antibody ACTR IC Antibody ACTR-IC Antibody ACTRIC Antibody ACV1C_HUMAN Antibody Acvr1c Antibody ACVRLK7 Antibody ALK 7 Antibody ALK-7 Antibody ALK7 Antibody
Information:	Target information shown above is from the UniProt Consortium.