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Anti-PCK2 Antibody

品牌：Antibodies

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規(guī)格：100μg

貨期：

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Anti-PCK2 Antibody

商品詳情參考文獻相關(guān)資料

Overview

Name:	Anti-PCK2 Antibody See all PCK2 primary antibodies
Description:	Goat polyclonal antibody to PCK2.
Applications:	ELISA, WB
Reactivity:	Human
Immunogen:	Synthetic peptide corresponding to Human PCK2 (internal region).
Sequence:	KPWKPGDKEPCAH
Host:	Goat
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	100 μg at 0.5 mg/ml.
Product Form:	Liquid
Formulation:	Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

Function:	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
Involvement in Disease:	Mitochondrial phosphoenolpyruvate carboxykinase deficiency: Metabolic disorder resulting from impaired gluconeogenesis. It is a rare disease with less than 10 cases reported in the literature. Clinical characteristics include hypotonia, hepatomegaly, failure to thrive, lactic acidosis and hypoglycemia. Autopsy reveals fatty infiltration of both the liver and kidneys. The disorder is transmitted as an autosomal recessive trait.
Sequence Similarities:	Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
Cellular Location:	Mitochondrion.
Database Links:	Entrez Gene: 5106?Human Omim: 261650?Human SwissProt: Q16822?Human Unigene: 75812?Human
Synonyms:	EC 4.1.1.32 Antibody GTP mitochondrial precursor Antibody HGNC:8725 Antibody mitochondrial Antibody Mitochondrial phosphoenolpyruvate carboxykinase 2 Antibody OTTHUMP00000164700 Antibody PCK2 Antibody PCKGM_HUMAN Antibody PE Antibody PEP carboxykinase Antibody PEPCK Antibody PEPCK deficiency mitochondrial Antibody PEPCK M Antibody PEPCK-M Antibody PEPCK2 Antibody Phosphoenolpyruvate carboxykinase 2 (mitochondrial) Antibody Phosphoenolpyruvate carboxykinase 2 mitochondrial Antibody Phosphoenolpyruvate carboxykinase [GTP] Antibody Phosphoenolpyruvate carboxylase Antibody Phosphopyruvate carboxylase Antibody
Information:	Target information shown above is from the UniProt Consortium.