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Anti-DIO2 Antibody

品牌：Antibodies

貨號：

規(guī)格：100μg

貨期：

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Anti-DIO2 Antibody

商品詳情參考文獻(xiàn) 相關(guān)資料

Name:	Anti-DIO2 Antibody See all DIO2 primary antibodies
Description:	Goat polyclonal antibody to DIO2.
Applications:	ELISA, IHC
Reactivity:	Mouse
Immunogen:	Synthetic peptide corresponding to Human DIO2 (internal region).
Sequence:	EVKKHQNQEDRC
Host:	Goat
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	100 μg at 0.5 mg/ml.
Product Form:	Liquid
Formulation:	Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Function:	Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine). Essential for providing the brain with appropriate levels of T3 during the critical period of development.
Tissue Specificity:	Expressed in mammary gland and in brain.
Sequence Similarities:	Belongs to the iodothyronine deiodinase family.
Post-Translational Modification:	Ubiquitinated by MARCH6, leading to its degradation by the proteasome. Deubiquitinated by USP20 and USP33 (By similarity).
Cellular Location:	Membrane.
Database Links:	Entrez Gene: 13371?Mouse SwissProt: Q9Z1Y9?Mouse Unigene: 21389?Mouse Unigene: 408815?Mouse
Synonyms:	5DII Antibody D2 Antibody Deiodinase, iodothyronine, type II Antibody DIO2 Antibody DIOII Antibody EC 1.97.1.10 Antibody IOD2_HUMAN Antibody ITDI2 Antibody SelY Antibody Thyroxine deiodinase, type II Antibody TXDI2 Antibody Type 2 DI Antibody Type 2 iodothyronine deiodinase Antibody Type II 5' deiodinase Antibody Type II iodothyronine deiodinase Antibody Type-II 5''-deiodinase Antibody
Information:	Target information shown above is from the UniProt Consortium.