熟女久久久,欧美国产激情二区三区-免费A片,中文伊人无码

您好，歡迎來到拜力生物網(wǎng)站！請(qǐng)登錄注冊(cè)

我的訂單 | 聯(lián)系我們 | 在線客服QQ：3012681483 | 客服電話：400-968-7988 | 工作時(shí)間：08:30-17:30

主營(yíng)產(chǎn)品： ELISA試劑盒、抗體、補(bǔ)體血清、兔補(bǔ)體、干擾素、小鼠測(cè)溫儀、進(jìn)口試劑、Quidel代理、Swant代理、PBL Assay Science代理

網(wǎng)站首頁(yè) 產(chǎn)品中心代理品牌新聞資訊資源中心關(guān)于我們

所在位置：首頁(yè) > 產(chǎn)品中心 > Antibodies > Antibodies產(chǎn)品

訂購(gòu)信息

上海拜力生物科技公司

Tel:400-968-7988 021-33779008

Anti-SILV Antibody

品牌：Antibodies

貨號(hào)：

規(guī)格：100μg

貨期：

應(yīng)用：

咨詢客服

立即購(gòu)買加入購(gòu)物車

Anti-SILV Antibody

商品詳情參考文獻(xiàn) 相關(guān)資料

Overview

Name:	Anti-SILV Antibody See all SILV primary antibodies
Description:	Goat polyclonal antibody to SILV.
Applications:	ELISA, WB
Reactivity:	Human
Immunogen:	Synthetic peptide corresponding to Human SILV (C terminal).
Sequence:	CPIGENSPLLSGQQ
Host:	Goat
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	100 μg at 0.5 mg/ml.
Product Form:	Liquid
Formulation:	Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

Function:	Plays a central role in the biogenesis of melanosomes. Involved in the maturation of melanosomes from stage I to II. The transition from stage I melanosomes to stage II melanosomes involves an elongation of the vesicle, and the appearance within of distinct fibrillar structures. Release of the soluble form, ME20-S, could protect tumor cells from antibody mediated immunity.
Tissue Specificity:	Preferentially expressed in melanomas. Some expression was found in dysplastic nevi. Not found in normal tissues nor in carcinomas. Normally expressed at low levels in quiescent ***** melanocytes but overexpressed by proliferating neonatal melanocytes and during tumor growth.
Sequence Similarities:	Belongs to the PMEL/NMB family.
Post-Translational Modification:	A small amount of P1/P100 (major form) undergoes glycosylation to yield P2/P120 (minor form). P2 is cleaved by a furin-like proprotein convertase (PC) in a pH-dependent manner in a post-Golgi, prelysosomal compartment into two disulfide-linked subunits: a large lumenal subunit, M-alpha/ME20-S, and an integral membrane subunit, M-beta. Despite cleavage, only a small fraction of M-alpha is secreted, whereas most M-alpha and M-beta remain associated with each other intracellularly. M-alpha is further processed to M-alpha N and M-alpha C. M-alpha C further undergoes processing to yield M-alpha C1 and M-alpha C3 (M-alpha C2 in the case of PMEL17-is or PMEL17-ls). Formation of intralumenal fibrils in the melanosomes requires the formation of M-alpha that becomes incorporated into the fibrils. Stage II melanosomes harbor only Golgi-modified Pmel17 fragments that are derived from M-alpha and that bear sialylated O-linked oligosaccharides.
Cellular Location:	Endoplasmic reticulum membrane. Golgi apparatus. Melanosome. Endosome > Multivesicular body. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Localizes predominantly to intralumenal vesicles (ILVs) within multivesicular bodies. Associates with ILVs found within the lumen of premelanosomes and melanosomes and particularly in compartments that serve as precursors to the striated stage II premelanosomes.
Database Links:	Entrez Gene: 6490?Human Omim: 155550?Human SwissProt: P40967?Human Unigene: 95972?Human
Synonyms:	95 kDa melanocyte specific secreted glycoprotein Antibody 95 kDa melanocyte-specific secreted glycoprotein Antibody D12S53E Antibody gp100 Antibody M-beta Antibody ME20 Antibody ME20 M/ME20 S Antibody ME20-M Antibody ME20-S Antibody ME20M Antibody ME20M/ME20S Antibody ME20S Antibody Melanocyte lineage specific antigen GP100 Antibody Melanocyte protein mel 17 Antibody Melanocyte protein Pmel 17 Antibody Melanocyte protein Pmel 17 precursor Antibody Melanocytes lineage-specific antigen GP100 Antibody Melanoma associated ME20 antigen Antibody Melanoma gp100 Antibody Melanoma-associated ME20 antigen Antibody Melanosomal matrix protein 17 Antibody Melanosomal matrix protein17 Antibody P1 Antibody p100 Antibody p26 Antibody PMEL Antibody PMEL 17 Antibody PMEL17 Antibody PMEL_HUMAN Antibody Premelanosome protein Antibody Secreted melanoma-associated ME20 antigen Antibody SI Antibody SIL Antibody SILV Antibody Silver (mouse homolog) like Antibody Silver homolog Antibody Silver locus protein homolog Antibody Silver, mouse, homolog of Antibody
Information:	Target information shown above is from the UniProt Consortium.