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Anti-Tenascin Antibody

品牌：Antibodies

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規(guī)格：100μg

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Anti-Tenascin Antibody

商品詳情參考文獻(xiàn) 相關(guān)資料

Overview

Name:	Anti-Tenascin Antibody See all Tenascin primary antibodies
Description:	Mouse monoclonal (T2H5) antibody to Tenascin.
Specificity:	The antibody T2H5 recognizes tenascin, a large hexameric extracellular matrix glycoprotein.
Applications:	IHC-P, IP, WB
Reactivity:	Human
Immunogen:	Protein preparation from a homogenate of a human mammary tumour specimen.
Host:	Mouse
Clonality:	Monoclonal
Clone:	T2H5
Isotype:	IgG1
Conjugate:	Unconjugated
Purification:	Protein A chromatography.
Concentration:	1 mg/ml
Purity:	> 95% (by SDS-PAGE)
Product Form:	Liquid
Formulation:	Supplied in Tris Buffered Saline, pH 8.0, with 15mM Sodium Azide.
Storage:	Store at 2-8°C.

Target

Function:	Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6.
Involvement in Disease:	Deafness, autosomal dominant, 56: A form of non-syndromic sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information. DFNA56 is characterized by progressive hearing impairment with post-lingual onset.
Sequence Similarities:	Belongs to the tenascin family.
Cellular Location:	Secreted > Extracellular space > Extracellular matrix.
Database Links:	Entrez Gene: 3371?Human Omim: 187380?Human SwissProt: P24821?Human Unigene: 143250?Human
Synonyms:	150 225 Antibody Cytotactin Antibody Glioma associated extracellular matrix antigen Antibody Glioma-associated-extracellular matrix antigen Antibody GMEM Antibody GP Antibody GP 150 225 Antibody GP 150-225 Antibody Hexabrachion Antibody HXB Antibody JI Antibody MGC167029 Antibody Miotendinous antigen Antibody Myotendinous antigen Antibody Neuronectin Antibody Tenascin Antibody Tenascin C Antibody Tenascin-C Antibody Tenascin-C isoform 14/AD1/16 Antibody TenascinC Antibody TENA_HUMAN Antibody TN Antibody TN C Antibody TN-C Antibody TNC Antibody
Information:	Target information shown above is from the UniProt Consortium.