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Anti-CD81 Antibody

品牌：Antibodies

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規(guī)格：100μg

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Anti-CD81 Antibody

商品詳情參考文獻相關資料

Overview

Name:	Anti-CD81 Antibody See all CD81 primary antibodies
Description:	Mouse monoclonal (M38) antibody to CD81.
Specificity:	The antibody M38 reacts with CD81, a 25 kDa member of the tetraspanin family, expressed on majority of cells.
Applications:	FC, IP, WB, IHC-P, ICC, FUNC
Reactivity:	Human, Cat, Rabbit
Immunogen:	MOLT-4 (human T-ALL cell line).
Host:	Mouse
Clonality:	Monoclonal
Clone:	M38
Isotype:	IgG1
Conjugate:	Unconjugated
Purification:	Protein A chromatography.
Concentration:	1 mg/ml
Purity:	> 95% (by SDS-PAGE)
Product Form:	Liquid
Formulation:	Supplied in Phosphate Buffered Saline, pH 7.4, with 15mM Sodium Azide.
Storage:	Store at 2-8°C.

Target

Function:	May play an important role in the regulation of lymphoma cell growth. Interacts with a 16-kDa Leu-13 protein to form a complex possibly involved in signal transduction. May act as the viral receptor for HCV.
Tissue Specificity:	Hematolymphoid, neuroectodermal and mesenchymal tumor cell lines.
Involvement in Disease:	Immunodeficiency, common variable, 6: A primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B-cells is usually in the normal range, but can be low.
Sequence Similarities:	Belongs to the tetraspanin (TM4SF) family.
Post-Translational Modification:	Not glycosylated.
Cellular Location:	Membrane.
Database Links:	Entrez Gene: 975?Human Omim: 186845?Human SwissProt: P60033?Human Unigene: 54457?Human
Synonyms:	26 kDa cell surface protein TAPA 1 Antibody 26 kDa cell surface protein TAPA-1 Antibody 26 kDa cell surface protein TAPA1 Antibody CD 81 Antibody CD81 Antibody CD81 antigen Antibody CD81 antigen (target of antiproliferative Antibody CD81 molecule Antibody CD81_HUMAN Antibody CVID6 Antibody S5.7 Antibody TAPA 1 Antibody TAPA1 Antibody Target of the antiproliferative Antibody Tetraspanin 28 Antibody Tetraspanin-28 Antibody Tetraspanin28 Antibody Tspan 28 Antibody Tspan-28 Antibody Tspan28 Antibody
Information:	Target information shown above is from the UniProt Consortium.