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Anti-CDCP1 Antibody

品牌：Antibodies

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規(guī)格：100μg

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Anti-CDCP1 Antibody

商品詳情參考文獻(xiàn) 相關(guān)資料

Overview

Name:	Anti-CDCP1 Antibody See all CDCP1 primary antibodies
Description:	Goat polyclonal antibody to CDCP1.
Applications:	ELISA, WB, IHC
Reactivity:	Human
Immunogen:	Synthetic peptide corresponding to Human CDCP1 (C terminal).
Sequence:	C-PLLNTQEPMEPAE
Host:	Goat
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	100 μg at 0.5 mg/ml.
Product Form:	Liquid
Formulation:	Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

Function:	May be involved in cell adhesion and cell matrix association. May play a role in the regulation of anchorage versus migration or proliferation versus differentiation via its phosphorylation. May be a novel marker for leukemia diagnosis and for immature hematopoietic stem cell subsets. Belongs to the tetraspanin web involved in tumor progression and metastasis.
Tissue Specificity:	Highly expressed in mitotic cells with low expression during interphase. Detected at highest levels in skeletal muscle and colon with lower levels in kidney, small intestine, placenta and lung. Up-regulated in a number of human tumor cell lines, as well as in colorectal cancer, breast carcinoma and lung cancer. Also expressed in cells with phenotypes reminiscent of mesenchymal stem cells and neural stem cells.
Post-Translational Modification:	Phosphorylated on tyrosine by kinases of the SRC family such as SRC and YES as well as by the protein kinase C gamma/PRKCG. Dephosphorylated by phosphotyrosine phosphatases. Also phosphorylated by suramin, a heparin analog. Tyrosine phosphorylated in response to dissociation of integrin alpha-6 beta-4 from laminin-5.
Cellular Location:	Cell membrane. Shedding may also lead to a soluble peptide.
Database Links:	Entrez Gene: 64866?Human Omim: 611735?Human SwissProt: Q9H5V8?Human Unigene: 476093?Human
Synonyms:	9030022E12Rik Antibody AA409659 Antibody CD 318 Antibody CD318 Antibody CD318 antigen Antibody CDCP 1 Antibody CDCP1 Antibody CDCP1_HUMAN Antibody CD_antigen=CD318 Antibody CUB domain containing protein 1 Antibody CUB domain-containing protein 1 Antibody E030027H19Rik Antibody FLJ13772 Antibody FLJ22375 Antibody FLJ22969 Antibody Membrane glycoprotein gp140 Antibody MGC31813 Antibody OTTHUMP00000164120 Antibody OTTHUMP00000209568 Antibody RGD1305578 Antibody SIMA 135 Antibody SIMA135 Antibody Subtractive immunization M plus HEp3 associated 135 kDa protein Antibody Subtractive immunization M plus HEp3-associated 135 kDa protein Antibody Transmembrane and associated with src kinases Antibody TRASK Antibody
Information:	Target information shown above is from the UniProt Consortium.