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Anti-AIF1 Antibody

品牌：Antibodies

貨號：

規(guī)格：100μg

貨期：

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Anti-AIF1 Antibody

商品詳情參考文獻(xiàn) 相關(guān)資料

Overview

Name:	Anti-AIF1 Antibody See all AIF1 primary antibodies
Description:	Goat polyclonal antibody to AIF1.
Applications:	ELISA, WB
Reactivity:	Human, Mouse, Rat
Immunogen:	Synthetic peptide corresponding to Human AIF1 (C terminal).
Sequence:	C-TGPPAKKAISELP
Host:	Goat
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	100 μg at 0.5 mg/ml.
Product Form:	Liquid
Formulation:	Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

Function:	Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play an role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation (By similarity).
Tissue Specificity:	Cardiac allograft, spleen and testis. Expressed by inflammatory cells (macrophages and neutrophils).
Cellular Location:	Cytoplasm > Cytoskeleton. Cell projection > Ruffle membrane. Cell projection > Phagocytic cup. Associated with the actin cytoskeleton at membrane ruffles and at sites of phagocytosis.
Database Links:	Entrez Gene: 199?Human Entrez Gene: 11629?Mouse Entrez Gene: 29427?Rat Omim: 601833?Human SwissProt: P55008?Human SwissProt: O70200?Mouse SwissProt: P55009?Rat Unigene: 76364?Human Unigene: 10747?Mouse Unigene: 32080?Rat
Synonyms:	AIF 1 Antibody AIF-1 Antibody Aif1 Antibody AIF1 protein Antibody AIF1_HUMAN Antibody Allograft inflammatory factor 1 Antibody Allograft inflammatory factor 1 splice variant G Antibody allograft inflammatory factor-1 splice variant Hara-1 Antibody balloon angioplasty responsive transcription Antibody BART 1 Antibody G1 Antibody G1 putative splice variant of allograft inflamatory factor 1 Antibody IBA 1 Antibody Iba1 Antibody interferon gamma responsive transcript Antibody Interferon responsive transcript 1 Antibody interferon responsive transcript factor 1 Antibody Ionized calcium binding adapter molecule 1 Antibody ionized calcium-binding adapter molecule Antibody Ionized calcium-binding adapter molecule 1 Antibody IRT 1 Antibody IRT1 Antibody Microglia response factor Antibody MRF1 Antibody Protein g1 Antibody
Information:	Target information shown above is from the UniProt Consortium.