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Anti-Exendin-4 ABS 012-20

品牌：

貨號：ABS 012-20

規(guī)格：200 μg

貨期：

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Anti-Exendin-4

商品詳情參考文獻(xiàn) 相關(guān)資料

Cat. No.: ABS 012-20
Product name: Anti-Exendin-4
Description: Mouse monoclonal antibody
Specificity: Specific for exendin-4. No cross-reactivity with GLP-1, GLP-2 (human) or glucagon coated on ELISA wells
Immunogen: Synthetic exendin-4?
Application: ELISA
Species reactivity (positive): Human
Species reactivity (negative): Not determined
Subclass: IgG1/k
Gene ID: 2740
Clone number: 20
Epitope: The epitope is in the 9-39 region of the peptide, and the antibody cross-reacts strongly with exendin (9-39)amide.
Content: Available in 200 μL and 1 mL size.1 mg/mL +/- 15%. See Certificate of Analysis for details.
Purification: Protein-A purified
Form: Liquid
Solvent: 0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Storage: 4-8oC without exposure to light. No precautions necessary during handling.
Target: Exendin-4 is a 39 amino acid peptide found in venom from the Gila monster?Heloderma suspectum.?It is a member of the glucagon-secretin family of peptide hormones and neuropeptides. Exendin-4 is a potent agonist of the GLP-1 receptor and hence a potent stimulator of insulin secretion.

Application 1: ELISA

ABS 012-20 binds to exendin-4 when coated on ELISA wells and reacts specifically with exendin-4 in solution giving a Ka of 1.6x10E8 in inhibition ELISA. The binding between ABS 012-20 and exendin-4 is disrupted by 4.5 M MgCl2.?